Neurobiology: Odorant receptors make scents
نویسندگان
چکیده
منابع مشابه
Small molecules make scents
smells.” Not all students of chemistry are drawn to the stenches and explosions in the laboratory. Fortunately, there are many organic molecules that actually smell nice. We experience these substances daily – using a perfumed shower gel, flavouring our meals with herbs, or burying our nose deep in a rose. Teaching the organic chemistry of natural scents should motivate even those who despise t...
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Stimulating arbitrary collections of as few as 300 neurons in the primary olfactory cortex of mice suffices for associative learning independent of any odor stimulation. Thus, programmed spatial relationships may not exist in piriform cortex, making flexible random associations the rule.
متن کاملTuning Insect Odorant Receptors
Citation: Wicher D (2018) Tuning Insect Odorant Receptors. Front. Cell. Neurosci. 12:94. doi: 10.3389/fncel.2018.00094 Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. A special property of this receptor type is the capability to adjust sensitivity of odor detection according to previous odor contacts. This article presents a cu...
متن کاملThe search for odorant receptors
The Question The first time I thought about olfaction was when I read a 1985 paper from Sol Snyder's group that discussed the unsolved question of how odors are detected in the nose (Pevsner et al., 1985). This paper opened up a fascinating new world for me. It was estimated that humans could perceive 10,000 or more chemicals as having distinct odors. Even more remarkably, subtle changes in an ...
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Odorant detection in insects involves heterodimers between an odorant receptor (OR) and a conserved seven-transmembrane protein called Or83b, but the exact mechanism of OR signal transduction is unclear. Two recent studies in Nature (Sato et al., 2008; Wicher et al., 2008) now reveal that these OR-Or83b heterodimers form odorant-gated ion channels, revealing a surprising new mode of olfactory t...
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ژورنال
عنوان ژورنال: Nature
سال: 2004
ISSN: 0028-0836,1476-4679
DOI: 10.1038/430511a